precautionary: Safety Diagnostics for Dose-Escalation Trial Designs

Enhances various R packages that support the design and simulation of phase 1 dose-escalation trials, adding diagnostics to examine the safety characteristics of these designs in light of expected inter-individual variation in pharmacokinetics and pharmacodynamics. See Norris (2020), "Retrospective analysis of a fatal dose-finding trial" <arXiv:2004.12755>.

Version: 0.1-2
Depends: magrittr, escalation, data.table
Imports: methods, dplyr, rlang, stringr, knitr, kableExtra
Suggests: rmarkdown, bookdown, tufte, testthat
Published: 2020-08-01
Author: David C. Norris ORCID iD [aut, cre, cph]
Maintainer: David C. Norris <david at precisionmethods.guru>
License: MIT + file LICENSE
URL: https://precisionmethods.guru/
NeedsCompilation: no
Materials: NEWS
CRAN checks: precautionary results

Downloads:

Reference manual: precautionary.pdf
Vignettes: Introduction to package 'precautionary'
Package source: precautionary_0.1-2.tar.gz
Windows binaries: r-devel: precautionary_0.1-2.zip, r-release: precautionary_0.1-2.zip, r-oldrel: not available
macOS binaries: r-release: precautionary_0.1-1.tgz, r-oldrel: precautionary_0.1-2.tgz
Old sources: precautionary archive

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